forestSV: structural variant discovery through statistical learning
نویسندگان
چکیده
منابع مشابه
Statistical Relational Learning through Structural Analogy and Probabilistic Generalization
Statistical Relational Learning through Structural Analogy and Probabilistic Generalization
متن کاملCombinatorial Optimization through Statistical Instance-Based Learning
Different successful heuristic approaches have been proposed for solving combinatorial optimization problems. Commonly, each of them is specialized to serve a different purpose or address specific difficulties. However, most combinatorial problems that model real world applications have a priori well known measurable properties. Embedded machine learning methods may aid towards the recognition ...
متن کاملStatistical physics of fracture: scientific discovery through high-performance computing
The paper presents the state-of-the-art algorithmic developments for simulating the fracture of disordered quasi-brittle materials using discrete lattice systems. Large scale simulations are often required to obtain accurate scaling laws; however, due to computational complexity, the simulations using the traditional algorithms were limited to small system sizes. We have developed two algorithm...
متن کاملA Statistical Learning Theory Framework for Supervised Pattern Discovery
This paper formalizes a latent variable inference problem we call supervised pattern discovery, the goal of which is to find sets of observations that belong to a single “pattern.” We discuss two versions of the problem and prove uniform risk bounds for both. In the first version, collections of patterns can be generated in an arbitrary manner and the data consist of multiple labeled collection...
متن کاملStatistical Learning in Drug Discovery via Clustering and Mixtures
In drug discovery, thousands of compounds are assayed to detect activity against a biological target. The goal of drug discovery is to identify compounds that are active against the target (e.g. inhibit a virus). Statistical learning in drug discovery seeks to build a model that uses descriptors characterizing molecular structure to predict biological activity. However, the characteristics of d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Methods
سال: 2012
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth.2085